Recombinant Human PDGFR alpha (N-GST tag)
Catalog No : IGX-RP974
366.40€
0.00€
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| Product name | Recombinant Human PDGFR alpha (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP974 | ||
| Supplier’s Catalog No | IGX-RP974 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 95 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | CD140A, PDGFR2, MGC74795, Rhe-PDGFRA | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PDGFRa (platelet-derived growth factor receptor a) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRa has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRa in renal cell types involved in fibrotic and sclerosing processes . PDGF and its receptor PDGFRa are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase . | ||
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