Recombinant Human PDGFR beta (N-GST tag)
Catalog No : IGX-RP975
366.40€
0.00€
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| Product name | Recombinant Human PDGFR beta (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP975 | ||
| Supplier’s Catalog No | IGX-RP975 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 104 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | JTK12; PDGFR; CD140B; PDGFR1 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description |  PDGFRß (platelet-derived growth factor receptor ?) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. PDGFRß deficient mice are hemorrhagic, severely anemic and exhibit a defect in kidney glomeruli function . However, absence of PDGFRß has no impact on major blood vessels and the heart. PDGFRß?expression and activity is elevated in several cancers and inhibition of PDGFRß activity blocks progression of renal carcinoma in an animal model . | ||
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