Recombinant Human PFTK1 (CDK14)/CyclinY (N-GST tag)
Catalog No : IGX-RP982
408.24€
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| Product name | Recombinant Human PFTK1 (CDK14)/CyclinY (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP982 | ||
| Supplier’s Catalog No | IGX-RP982 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 72 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PFTK1: CDK14; PFTAIRE1 Cyclin Y: CCNY; C10orf9; CBCP1; CCNX; CFP1 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PFTK1 is a member of the CDC2 - related protein kinase family which is expressed primarily in the postnatal and adult nervous system . PFTK1 is expressed at high levels in brain, pancreas, kidney, heart, testis, and ovary. PFTK1 amino acid residue ser119 is required for its interaction with all four 14-3-3 isoforms, while ser120 may contribute slightly to PFTK1 binding . PFTK1 acts as a cyclin-dependent kinase that regulates cell cycle progression and cell proliferation. Overexpression of PFTK1 predicts resistance to chemotherapy in patients with oesophageal squamous cell carcinoma. | ||
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