Recombinant Human PI3K (p110 alpha/p55 gamma) (N-His tag)
Catalog No : IGX-RP985
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| Product name | Recombinant Human PI3K (p110 alpha/p55 gamma) (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP985 | ||
| Supplier’s Catalog No | IGX-RP985 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 111 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | p110a: PI3K, p110-alpha p55g: PIK3R3, p55, p55-GAMMA, FLJ41892 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PI3K (p110alpha/p55gamma) or Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position which serve as second messengers in growth signaling pathways. PI3K comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in the PI3K has been associated with insulin resistance and plays an important role in glucose homeostasis in vivo . PI3K also plays an essential role in the development and induction of mast cells in normal and pathogenic immune responses . | ||
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