Recombinant Human PI3K (p110 delta/p85 alpha) (N-His tag)
Catalog No : IGX-RP989
291.09€
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| Product name | Recombinant Human PI3K (p110 delta/p85 alpha) (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP989 | ||
| Supplier’s Catalog No | IGX-RP989 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 111 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | p110δ: p110δp85α: PIK3R1, GRB1, p85-ALPHA | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PI3K (p110d/p85a) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring . PI3K (p110d/p85a) plays a role in oncogenic transformation, and is consistently expressed at a high level in blast cells from AML. PI3K (p110d/p85a) can play a selective role in the amplification of phosphatidylinositol (3,4,5) trisphosphate (PIP3) levels that lead to neutrophil polarization, and regulates directional migration, but not random locomotion . PI3K (p110d/p85a) signaling pathway is involved in immune responses relevant to the pathogenesis of rheumatoid arthritis and other inflammatory diseases. | ||
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