Recombinant Human PI3K (p120 gamma) (N-His tag)
Catalog No : IGX-RP990
291.09€
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| Product name | Recombinant Human PI3K (p120 gamma) (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP990 | ||
| Supplier’s Catalog No | IGX-RP990 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 121 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | p110γ: PI3K, PIK3, PI3CG, PI3Kgamma | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PI3K (p120?) is a member of the PI3K family that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. PI3K (p120?) is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, PI3K (p120?) is thought to play a pivotal role in the regulation of cytotoxicity in NK cells . In addition, PI3K (p120?) plays an inhibitory role in inflammatory mediator-induced human vascular smooth muscle cell calcification through regulating alkaline phosphatase expression . | ||
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