Recombinant Human PI4KB (N-GST tag)
Catalog No : IGX-RP993
366.40€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | Recombinant Human PI4KB (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP993 | ||
| Supplier’s Catalog No | IGX-RP993 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 120 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PI4K-BETA, pi4K92, PI4Kbeta, PI4KIIIbeta | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Â PI4KB is a member of the phosphatidylinositol 4-kinase family (PI4K) and is the first committed step in the production of the second messenger inositol-1,4,5-trisphosphate (PIP3). PI4KB regulates the golgi disintegration/reorganization during mitosis possibly via the phosphorylation of phosphatidylinositol . PI4KB is a type III enzyme that is sensitive to wortmannin and is responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. PI4KB is critical for glucose-induced insulin secretion due to its capacity to regulate the release of secretory granules . PI4KB inhibits the insulin-stimulated translocation of glucose transporter-4 in mouse adipocytes through its interaction with neuronal calcium sensor-1. | ||
Product Details
© 2020 Imugex All Rights Reserved