Recombinant Human PIK3C3 (Vps34) (N-GST tag)
Catalog No : IGX-RP996
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Product name | Recombinant Human PIK3C3 (Vps34) (N-GST tag) | ||
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Catalog No | IGX-RP996 | ||
Supplier’s Catalog No | IGX-RP996 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 128 |
Storage | -70°C | ||
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Other names | VPS34, hVps34, MGC61518 | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | PIK3C3 or phosphoinositide-3-kinase is a member of the PI 3-kinase family that mediates the active diversion of proteins from the secretory pathway to vacuoles. PIK3C3 are involved in both receptor-mediated signal transduction and intracellular trafficking. In yeast, the vps34 gene product is a PI 3-kinase. PIK3C3 has a substrate specificity and ion requirements that are distinct from the other known mammalian PI 3-kinases . PIK3C3 mediate catalysis on membranes and suppress futile adenosine triphosphatase cycles. PIK3C3 appears to alternate between a closed cytosolic form and an open form on the membrane . |
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