Recombinant Human PIM1 (N-GST tag)
Catalog No : IGX-RP997
366.40€
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| Product name | Recombinant Human PIM1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP997 | ||
| Supplier’s Catalog No | IGX-RP997 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 62 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PIM | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PIM1 is a proto-oncogene that belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from Moloney murine leukemia virus induced T-cell lymphomas in mice, PIM1 is involved in the control of cytokine-mediated cell proliferation, differentiation and survival of lymphoid and myeloid cells as well as others . Expression of PIM1 can be stimulated by a variety of growth factors and is regulated at four different levels: transcriptional, post-transcriptional, translational and post-translational . Expression of PIM1 is mediated through activation of the JAK/STAT pathway. | ||
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