Recombinant Human PKAc alpha (N-GST tag)
Catalog No : IGX-RP1004
366.40€
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Product name | Recombinant Human PKAc alpha (N-GST tag) | ||
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Catalog No | IGX-RP1004 | ||
Supplier’s Catalog No | IGX-RP1004 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 69 |
Storage | -70°C | ||
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Other names | PKAa; cAPKa; MGC48865; MGC102831 | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | The catalytic subunit C-alpha of PKA (PKAca) is a member of the Ser/Thr protein kinase family and has been assigned to chromosome region 19p13.1 . Null mutation in PKAca leads to early postnatal lethality in the majority of C-alpha knockout mice. Surprisingly, a small percentage of C-alpha knockout mice, although runted, survived to adulthood. In these animals, compensatory increases in C-beta levels occurred in brain whereas many tissues, including skeletal muscle, heart, and sperm, contained less than 10% of the normal PKA activity . |
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