Recombinant Human PKC iota (N-GST tag)
Catalog No : IGX-RP1014
291.09€
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| Product name | Recombinant Human PKC iota (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1014 | ||
| Supplier’s Catalog No | IGX-RP1014 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 98 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PRKCI; DXS1179E; MGC26534; nPKC-iota | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PKC? is a member of the protein kinase C family of serine-threonine kinases. The amino acid sequence of PKC? showed greatest homology to PKCzeta, with 72% identity overall rising to 84% in the catalytic domain. Protein kinase C iota (PKC?) has been implicated in Ras signaling and is a critical downstream effector of oncogenic Ras in the colonic epithelium. Transgenic mice expressing constitutively active PKC? in the colon are highly susceptible to carcinogen-induced colon carcinogenesis . | ||
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