Recombinant Human PKC theta (N-GST tag)
Catalog No : IGX-RP1017
366.40€
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| Product name | Recombinant Human PKC theta (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1017 | ||
| Supplier’s Catalog No | IGX-RP1017 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 110 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PRKCQ, PRKCT, MGC126514, MGC141919, nPKC-theta | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Protein Kinase C, theta (PKC?) is important component in the intracellular signaling cascade . Recent studies have suggested that local accumulation of fat metabolites inside skeletal muscle may activate a serine kinase cascade involving PKC-theta leading to defects in insulin signaling and glucose transport in skeletal muscle . Insulin resistance plays a primary role in the development of type 2 diabetes and may be related to alterations in fat metabolism. PKC-theta is a crucial component mediating fat-induced insulin resistance in skeletal muscle and is a potential therapeutic target for the treatment of type 2 diabetes . | ||
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