Recombinant Human PKC zeta (N-GST tag)

Catalog No : IGX-RP1018
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Product name Recombinant Human PKC zeta (N-GST tag)
Catalog No IGX-RP1018
Supplier’s Catalog No IGX-RP1018
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 93
Storage -70°C
Other names PRKCZ; PRKCZ; PKC2
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description PKC? is an atypical isoform of the PKC family. PKC? is found in both particulate and soluble fractions and cannot be activated by phorbol ester. Overexpression of PKC? and subsequent phorbol ester treatment abolished phorbol ester-induced reduction in cell proliferation . Overexpression of PKC? also potentiates phorbol ester-induced mitogen-activated protein (MAP) kinase activation in a PKC-dependent manner. PKC? is an upstream modulator of p70S6K, an important regulator of cell proliferation .Â