Recombinant Human PKN1/PRK1 (N-GST tag)
Catalog No : IGX-RP1020
366.40€
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| Product name | Recombinant Human PKN1/PRK1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1020 | ||
| Supplier’s Catalog No | IGX-RP1020 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 115 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PRK1, DBK, PKN1, PKN, MGC46204, PAK1, PRKCL1, PKC-L1 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PKN1/PRK1 belongs to the protein kinase C superfamily which is activated by Rho family of small G proteins. PKN1/PRK1 is known to mediate the Rho-dependent signaling pathway and it can be activated by phospholipids and by limited proteolysis . PDPK1/PDK may also mediate insulin signals to the actin cytoskeleton and the proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggest its role in signal transduction related to apoptosis. PKN1/PRK signaling stimulates AR activity in the presence of adrenal androgens and in the presence of an AR antagonist . | ||
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