Recombinant Human PKN2/PRK2 (N-GST tag)
Catalog No : IGX-RP1021
366.40€
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| Product name | Recombinant Human PKN2/PRK2 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1021 | ||
| Supplier’s Catalog No | IGX-RP1021 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 145 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PRKCL2, PKN2, PRK2, PAK2, Pak-2, PRO2042, MGC71074, MGC150606 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PKN2 (also known as PRK2) is a Rho effector and a member of the protein kinase C superfamily of serine/threonine kinases. PKN2 is an essential regulator of both entry into mitosis and exit from cytokinesis in HeLa S3 cells . PKN2 is required for abscission of the midbody at the end of the cell division cycle and for phosphorylation and activation of Cdc25B, the phosphatase required for activation of mitotic cyclin/Cdk1 complexes at the G2/M transition. C-terminus of PKN2 could be a potential drug target for effector-specific pharmacological intervention of Rho-medicated biological processes . | ||
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