Recombinant Human PLK1 (N-His tag)
Catalog No : IGX-RP1023
366.40€
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Product name | Recombinant Human PLK1 (N-His tag) | ||
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Catalog No | IGX-RP1023 | ||
Supplier’s Catalog No | IGX-RP1023 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 70 |
Storage | -70°C | ||
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Other names | STPK13 | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | PLK1 is a member of the Polo-Like Kinase family that localize to centrosomes or spindle pole bodies and undergo dramatic subcellular relocation during the cell cycle. Deregulated activities of PLKs often result in abnormalities in centrosome duplication, maturation, and/or microtubule dynamics . PLKs also regulate the function of the Golgi complex. Deregulated expression of human PLK1 is strongly correlated with the development of many types of malignancies, and ectopic expression of PLK1 dominant negative protein leads to rapid cell death . |
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