Recombinant Human PYK2 (N-His tag)
Catalog No : IGX-RP1031
366.40€
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| Product name | Recombinant Human PYK2 (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1031 | ||
| Supplier’s Catalog No | IGX-RP1031 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 39 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | FAK2, PTK2B, CADTK, FADK2, CAKB, PKB, PTK, RAFTK; PYK2 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | PYK2 (also known as FAK2/RAFTK) is a member of the focal adhesion PTK family. PYK2/FAK2 can be activated by a variety of extracellular signals that elevate intracellular calcium concentration, and by stress signals . Unlike FAK, which is widely expressed in various tissues and links transmembrane integrin receptors to intracellular pathways, PYK2/FAK2 is expressed mainly in the central nervous system and in cells derived from hematopoietic lineages. In osteoclasts, although FAK is expressed, PYK2/FAK2 appears to be the predominant mediator of integrin alpha(v)beta3 signaling events that influence osteoclast physiology and pathology . | ||
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