Recombinant Human RIPK1 (N-GST tag)
Catalog No : IGX-RP1035
617.44€
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Product name | Recombinant Human RIPK1 (N-GST tag) | ||
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Catalog No | IGX-RP1035 | ||
Supplier’s Catalog No | IGX-RP1035 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 108 |
Storage | -70°C | ||
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Other names | RCK; MAP3K19 | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | Â RIPK1 or Receptor Interacting Protein Kinase 1 is a serine/threonine kinase that was originally identified as interacting with the cytoplasmic domain of FAS. RIPK1 has been deemed as an important element in the signal transduction machinery that mediates programmed cell death. RIPK1 has been shown to interact with TRADD, TRAF1 TRAF2 and TRAF3 and TRADD can act as an adaptor protein to recruit RIPK1 to the TNFR1 complex in a TNF-dependent process . TNFalpha is capable of activating the noncanonical NF-kB pathway, but this activation of this pathway is negatively regulated by RIPK1 . |
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