Recombinant Human ROCK2 (N-His tag)
Catalog No : IGX-RP1041
366.40€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | Recombinant Human ROCK2 (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1041 | ||
| Supplier’s Catalog No | IGX-RP1041 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 66 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | KIAA0619; ROCK-II; ROKalpha | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | ROCK2 is a ubiquitously expressed serine/threonine kinase localized in the nucleus that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element . ROCK2 is an immediate downstream target of the small GTPase RhoA. ROCK2 may play a pivotal role in cardiovascular diseases such as vasospastic angina, ischemic stroke, and heart failure. Inhibition of ROCKs by statins or other selective inhibitors leads to the upregulation and activation of endothelial nitric oxide synthase (eNOS) and reduction of vascular inflammation and atherosclerosis . | ||
Product Details
© 2020 Imugex All Rights Reserved