Recombinant Human RON (N-GST tag)
Catalog No : IGX-RP1042
366.40€
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| Product name | Recombinant Human RON (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1042 | ||
| Supplier’s Catalog No | IGX-RP1042 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 71 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | MST1R, PTK8, CDw136 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | RON is a macrophage stimulating 1 receptor c-met-related tyrosine kinase . RON receptor tyrosine kinase interacts with HYAL2 receptor protein, rendering it functionally inactive. HYAL2 is a candidate tumor-suppressor glycosylphosphatidylinositol-anchored cell-surface protein that serves as an entry receptor for jaagsiekte sheep retrovirus, a virus that causes contagious lung cancer in sheep that is morphologically similar to human bronchioloalveolar carcinoma. It was shown that RON liberated from the association with HYAL2 becomes functionally active and activates the Akt and mitogen-activated protein kinase pathways . | ||
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