Recombinant Human SIK (N-GST tag)
Catalog No : IGX-RP1055
366.40€
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| Product name | Recombinant Human SIK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1055 | ||
| Supplier’s Catalog No | IGX-RP1055 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 61 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | SNF1LK, MSK, SIK1 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | SIK is a protein kinase that is involved in regulating AMPK-related kinases . SIK may mediate the physiological effects of LKB1, including its tumour suppressor function. SIK is also involved in signaling by various proteins like STRAD, NUAK1, NUAK2, BRSK1, BRSK2, QIK, QSK, SIK, MARK1, MARK2, MARK3, MARK4 and MELK that are related to AMPK. Activation of SIK1 by phosphorylation on thr322 can lead to an increase in the catalytic activity of sodium/potassium ATPase alpha subunit at the plasma membrane . This results in an increase in intracellular sodium in intact mammalian cells. | ||
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