Recombinant Human SNRK (N-GST tag)

Catalog No : IGX-RP1058
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Product name Recombinant Human SNRK (N-GST tag)
Catalog No IGX-RP1058
Supplier’s Catalog No IGX-RP1058
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 110
Storage -70°C
Other names HSNFRK, SNFRK, KIAA0096
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description  SNRK or sucrose non-fermenting related kinase is a member of the sucrose nonfermenting (SNF)-related kinase family of serine/threonine kinases which acts as a kinase and displays autophosphorylation activity . SNRK act as a substrate for the LKB1 tumor suppressor which phosphorylated SNRK at residue thr173 in which LKB1 is required for phosphorylation and activation of SNRK in HeLa cells and required STRAD and MO25 LKB1 complex-associated subunits. Snrk-1 is involved in multiple steps of angioblast development and acts via notch signaling pathway in artery-vein-specification in vertebrates .