Recombinant Human SRC (N-GST tag)

Catalog No : IGX-RP1062
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Product name Recombinant Human SRC (N-GST tag)
Catalog No IGX-RP1062
Supplier’s Catalog No IGX-RP1062
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 83
Storage -70°C
Other names ASV; SRC1; c-SRC; p60-Src
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates . SRC is overexpressed and activated in a large number of human malignancies and has been linked to the development of cancer and progression to distant metastases . In addition to increasing cell proliferation, a key role of SRC in cancer seems to be the ability to promote invasion and motility, functions that might contribute to tumour progression.Â