Recombinant Human STK39 (STLK3) (N-His tag)

Catalog No : IGX-RP1073
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Product name Recombinant Human STK39 (STLK3) (N-His tag)
Catalog No IGX-RP1073
Supplier’s Catalog No IGX-RP1073
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 63
Storage -70°C
Other names STK39; STLK3; DCHT; DKFZp686K05124; PASK; SPAK
Grade Highly Purified
Purity 70% - 90%
Form 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description STK39 (also known as serine threonine kinase 39) is involved in the cellular stress response pathway. STK39 is activated in response to hypotonic stress leading to phosphorylation of several cation-chloride-coupled co-transporters. STK39 activates the p38 MAP kinase pathway and its interaction with p38 decreases during cellular stress . STK39 acts as an intermediate in the response to cellular stress. STK39 is also an independent risk factor for hypertension in men and its intragenic SNPs can interact and function in the control of blood pressure .