Recombinant Human TGFBR1 (ALK5) (N-GST tag)
Catalog No : IGX-RP1082
366.40€
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| Product name | Recombinant Human TGFBR1 (ALK5) (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1082 | ||
| Supplier’s Catalog No | IGX-RP1082 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 66 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | AAT5, ALK5, SKR4, ALK-5, LDS1A, LSD2A, TGFR-1, ACVRLK4 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | TGFßR1 or transforming growth factor, beta-receptor 1 is a member of the TGFß receptor subfamily and is a ser/thr protein kinase that forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. Mutations in TGFßR1gene have been associated with Marfan syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors . TGFßR1-dependent signaling is required for angiogenesis but not for the development of hematopoietic progenitor cells and functional hematopoiesis . | ||
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