Recombinant Human TGFBR2 (N-GST tag)

Catalog No : IGX-RP1083
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Product name Recombinant Human TGFBR2 (N-GST tag)
Catalog No IGX-RP1083
Supplier’s Catalog No IGX-RP1083
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 68
Storage -70°C
Other names AAT3, FAA3, MFS2, RIIC, HNPCC6, TGFR-2, TGFbeta-RII, TAAD2
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description TGFßR2 is a member of the TGFß receptor subfamily and is a ser/thr protein kinase. TGFßR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses . The TGFßR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-beta type II receptor. Mutations in TGFßR2 gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors .