Recombinant Human TNIK (N-GST tag)

Catalog No : IGX-RP1087
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Product name Recombinant Human TNIK (N-GST tag)
Catalog No IGX-RP1087
Supplier’s Catalog No IGX-RP1087
Supplier ImuGeX
Source antigen Insect cells
Reactivity Human
Cross reactivity
Applications
Molecular weight 67
Storage -70°C
Other names (None)
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description TNIK or TRAF2 and NCK interacting kinase is characterized by an N-terminal kinase domain and a C-terminal GCK domain that serves a regulatory function . TNIK is mainly expression in brain, heart, and spleen and it is a specific effector of RAP2 which regulate actin cytoskeleton . TNIK is autophosphorylated in a manner dependent upon lys54 in the ATP-binding pocket of its kinase domain and plays a main role in cytoskeleton regulation.