Recombinant Human TRKA (N-GST tag)
Catalog No : IGX-RP1089
366.40€
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| Product name | Recombinant Human TRKA (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1089 | ||
| Supplier’s Catalog No | IGX-RP1089 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 66 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | NTRK1; MTC; TRK; TRK1; p140-TrkA; DKFZp781I14186 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | TRKA is a member of the trk proto-oncogene family and encodes a 140-kilodalton, membrane-spanning protein tyrosine kinase that is the functional receptor for nerve growth factor (NGF). NGF elicits the rapid phosphorylation of gp140trk on tyrosine residues leading to increased c-Fos expression, DNA synthesis and morphologic transformation . A decreased expression of TRKA on the striatal cholinergic neurons has been observed which may contribute, when it reaches a crucial threshold, to the death of cholinergic neurons observed in Alzheimer disease . | ||
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