Recombinant Human TXK (N-GST tag)
Catalog No : IGX-RP1096
366.40€
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| Product name | Recombinant Human TXK (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1096 | ||
| Supplier’s Catalog No | IGX-RP1096 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 53 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | RLK; TKL; BTKL; PTK4; PSCTK5; MGC22473 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | TXK or RLK is a member of the TEC family of non-receptor tyrosine kinases. TXK is expressed in T-cells and is an important component of signaling pathways downstream of lymphocyte antigen receptor. TXK is phosphorylated in response to T-cell receptor stimulation and can be activated by phosphorylation by Src family kinases. However, TXK is phosphorylated independent of PI-3K activity . Excessive TXK protein expression is seen in patients with Behcet's disease. Over production of TXK leads to increased Th1 cell function that is involved in the pathogenesis of Behcet’s disease . | ||
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