Recombinant Human TYK2 (JTK1) (N-GST tag)
Catalog No : IGX-RP1097
366.40€
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| Product name | Recombinant Human TYK2 (JTK1) (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1097 | ||
| Supplier’s Catalog No | IGX-RP1097 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 110 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | PSCTK4, MGC126760, MGC126762 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | TYK2 is a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families which associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. TYK2 play a role in anti-viral immunity and TYK2 plays an indispensable role in controlling responses to multiple cytokines in humans . Tyk2 contributes selectively to signals triggered by various biologic stimuli and cytokine receptors and TYK2 is an important regulator of lymphoid tumor surveillance . | ||
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