Recombinant Human ULK3 (N-His tag)
Catalog No : IGX-RP1101
408.24€
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Product name | Recombinant Human ULK3 (N-His tag) | ||
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Catalog No | IGX-RP1101 | ||
Supplier’s Catalog No | IGX-RP1101 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 51 |
Storage | -70°C | ||
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Other names | DKFZP434C131 | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM sodium, pHosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | Â ULK3 or unc-51-like kinase 3 is a member of the serine/threonine kinase family that is involved in the SHH signaling pathway as a positive regulator of GLI proteins . ULK3 enhances endogenous and over-expressed GLI transcriptional activity in cultured cells and alters its subcellular localization. Furthermore, ULK3 phosphorylates GLI proteins in vitro. ULK3 is widely expressed and its expression is higher in a number of tissues where SHH signaling is known to be active, again suggesting that ULK3 is involved in the SHH pathway as a positive regulator of GLI proteins. |
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