Recombinant Rat BTK (N-His tag)
Catalog No : IGX-RP1114
366.40€
0.00€
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| Product name | Recombinant Rat BTK (N-His tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1114 | ||
| Supplier’s Catalog No | IGX-RP1114 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Rat | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 105 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | AT; ATK; BPK; XLA; IMD1; AGMX1; PSCTK | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors .Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a desirable target for potential anti-cancer, anti-inflammatory and anti-viral agents as well as other treatments . | ||
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