Recombinant Rat CAMKK1 (N-GST tag)
Catalog No : IGX-RP1117
366.40€
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| Product name | Recombinant Rat CAMKK1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1117 | ||
| Supplier’s Catalog No | IGX-RP1117 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Rat | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 88 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | CaMKK1; CaMKK alpha; CaM-kinase IV kinase | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | CAMKK1 or CAMKKalpha is a Ca(2+)/calmodulin-dependent protein kinase that activates CAM-kinases I and IV via phosphorylation of their Thr(177) and Thr(196) residues, respectively. Recent studies have shown that the activity of CAMKK1 is decreased upon phosphorylation by cAMP-dependent protein kinase (PKA) The CAMKKalpha has been identified in intact cells as AMPKKs, predicting a significant role for this kinase in regulating AMPK activity in vivo. It has been shown that 2-deoxyglucose- and ionomycin-stimulated AMPK activity is substantially reduced in HeLa cells transfected with small interfering RNAs specific for CAMKKalpha . | ||
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