Recombinant Mouse EPHA1 (N-GST tag)

Catalog No : IGX-RP1118
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Product name Recombinant Mouse EPHA1 (N-GST tag)
Catalog No IGX-RP1118
Supplier’s Catalog No IGX-RP1118
Supplier ImuGeX
Source antigen Insect cells
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 71
Storage -70°C
Other names EPH; EPHT; EPHT1
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description  EPHA1 is a member of the Eph family of receptor tyrosine kinases that have been implicated in mediating developmental events, particularly in the nervous system . Receptors in the Eph subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. EPHA1 seems to be a marker of the differentiated normal epidermis and its downregulation in nonmelanoma skin cancer may contribute to carcinogenesis of these very frequent human tumors. EPHA1 represents a new potential prognostic marker and therapeutic target in nonmelanoma skin cancer .Â