Recombinant Mouse HIPK2 (N-GST tag)
Catalog No : IGX-RP1122
366.40€
0.00€
Shipping cost plus VAT not included , delivery in 7-14 business days
| Product name | Recombinant Mouse HIPK2 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1122 | ||
| Supplier’s Catalog No | IGX-RP1122 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Mouse | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 72 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | Stank; 1110014O20Rik; B230339E18Rik | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | Â HIPK2 is a conserved serine/threonine nuclear kinase that interacts with homeodomain transcription factors. HIPK2 enhances expression of p53 target genes that resulting in growth arrest and the enhancement of UV-induced apoptosis that could be inhibited by antisense to HIPK2 . HIPK2 as a target for MDM2 mediated ubiquitin-dependent degradation that only occurred in growth-arresting conditions when MDM2 was efficiently induced by p53 . The knockdown of HIPK2 using small interfering RNA reduced p53 binding and activation of p53R2 that resulting in impaired UV-induced DNA repair. | ||
Product Details
© 2020 Imugex All Rights Reserved