Recombinant Mouse JNK1 (N-GST tag)
Catalog No : IGX-RP1123
366.40€
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| Product name | Recombinant Mouse JNK1 (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1123 | ||
| Supplier’s Catalog No | IGX-RP1123 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Mouse | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 71 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | JNK; PRKM8; SAPK1; AI849689; JNK1A2; JNK21B1/2 | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | JNK1 is a member of the MAP kinase group that is activated by dual phosphorylation at thr and tyr residues during exposure to stress such as UV irradiation. JNK1 binds to the c-Jun transactivation domain and phosphorylates it on Ser-63 and Ser-73 . JNK1 has been shown to play an important role in disease processes. Activation of JNK1 results in defects in myotube viability and integrity leading to dystrophic myofiber destruction . JNK1 activity is also abnormally elevated in obesity and removal of JNK1 results in decreased adiposity and significantly improved insulin sensitivity. | ||
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