Recombinant Rat MET (N-GST tag)
Catalog No : IGX-RP1125
366.40€
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| Product name | Recombinant Rat MET (N-GST tag) | ||
|---|---|---|---|
| Catalog No | IGX-RP1125 | ||
| Supplier’s Catalog No | IGX-RP1125 | ||
| Supplier | ImuGeX | ||
| Source antigen | Insect cells | ||
| Reactivity | Rat | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 74 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | HGFR | ||
| Grade | Highly Purified | ||
| Purity | 70% - 90% | ||
| Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | 70% - 90% | ||
| Description | MET is a proto-oncogene that encodes a transmembrane growth factor receptor which is a heterodimer of two disulphide linked chains of 50 kd (alpha) and 145 kd (beta). MET is widely expressed in the kidney, brain, lung, skin, and embryonic tissue . Hepatocyte growth factor (HGF) binds to MET and activates its tyrosine kinase activity. MET is overexpressed and activated in a variety of human cancers including pancreatic, colon, gastric, cervical and ovarian cancers and has been shown to be involved in tumor cell migration and invasion . | ||
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