Recombinant Mouse NEK1 (N-GST tag)

Catalog No : IGX-RP1127
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Product name Recombinant Mouse NEK1 (N-GST tag)
Catalog No IGX-RP1127
Supplier’s Catalog No IGX-RP1127
Supplier ImuGeX
Source antigen Insect cells
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 85
Storage -70°C
Other names D8Ertd790e; kat; MGC189817
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description NEK1 or NIMA (never in mitosis gene a)-related kinase 1 is a serine/threonine kinase involved in cell cycle regulation and is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. NEK1 is involved early in the DNA damage response pathway . NEK1 cycles through the nucleus via its nuclear localization and export signals . NEK1 protein participates in different signaling pathways to regulate diverse cellular processes and plays an important role in the kidney where it has opened a new avenue for studying cystogenesis and identifying possible modes of therapy.