Recombinant Mouse PAK3 (N-GST tag)
Catalog No : IGX-RP1128
366.40€
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Product name | Recombinant Mouse PAK3 (N-GST tag) | ||
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Catalog No | IGX-RP1128 | ||
Supplier’s Catalog No | IGX-RP1128 | ||
Supplier | ImuGeX | ||
Source antigen | Insect cells | ||
Reactivity | Mouse | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 89 |
Storage | -70°C | ||
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Other names | Stk4, mPAK-3, Pak65beta, Pak65alpha | ||
Grade | Highly Purified | ||
Purity | 70% - 90% | ||
Form | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol. | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | 70% - 90% | ||
Description | PAK3 is a member of the family of serine/threonine p21-activating kinases that serve as targets for the small GTP binding proteins Cdc42 and RAC . The PAK family of proteins have been implicated in a wide range of biological activities and are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK3 seems to be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. A point mutation in PAK3 gene has been linked to nonsyndromic X-linked mental retardation . |
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