Recombinant Mouse PDGFR alpha (N-GST tag)

Catalog No : IGX-RP1129
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Product name Recombinant Mouse PDGFR alpha (N-GST tag)
Catalog No IGX-RP1129
Supplier’s Catalog No IGX-RP1129
Supplier ImuGeX
Source antigen Insect cells
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 100
Storage -70°C
Other names CD140a; Pdgfr-2; AI115593
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description PDGFRa (platelet-derived growth factor receptor A) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRa has been linked to developmental abnormalities in vertebrate models and has been implicated in multiple disease states in humans. There is widespread expression of PDGFRa in renal cell types involved in fibrotic and sclerosing processes. PDGF and its receptor PDGFRa are inducers of fibrosis in the repair phase of inflammatory bowel disease and they may also be involved in the active inflammatory phase .