Recombinant Mouse TGFBR2 (N-GST tag)

Catalog No : IGX-RP1135
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Product name Recombinant Mouse TGFBR2 (N-GST tag)
Catalog No IGX-RP1135
Supplier’s Catalog No IGX-RP1135
Supplier ImuGeX
Source antigen Insect cells
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 69
Storage -70°C
Other names 1110020H15Rik; AU042018; DNIIR; RIIDN; TbetaR-II; TbetaRII; TBR-II
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description TGFBR2 is a member of the TGFbeta receptor subfamily and is a ser/thr protein kinase. TGFBR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses . The TGFBR2 receptor transmits signals from the cell surface to the nucleus and provides instructions for making transforming growth factor (TGF)-beta type II receptor. Mutations in TGFBR2 gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors .