Recombinant Mouse TTBK2 (N-GST tag)

Catalog No : IGX-RP1136
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Product name Recombinant Mouse TTBK2 (N-GST tag)
Catalog No IGX-RP1136
Supplier’s Catalog No IGX-RP1136
Supplier ImuGeX
Source antigen Insect cells
Reactivity Mouse
Cross reactivity
Applications
Molecular weight 88
Storage -70°C
Other names mKIAA0847; TTBK; TTBK1; TTK
Grade Highly Purified
Purity 70% - 90%
Form 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Reactivity life 6 months
Note For reserch purpose only
Purity 70% - 90%
Description TTBK2 or tau tubulin kinase 2 is a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. TTBK2 is a member of the casein kinase (CK1) group of eukaryotic protein kinases that is involved in tau phosphorylation and aggregation . Mutations in TTBK2 cause spinocerebellar ataxia type 11 (SCA11) (a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem) .