Recombinant Human PTH
Catalog No : IGX-RP1168
613.26€
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Product name | Recombinant Human PTH | ||
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Catalog No | IGX-RP1168 | ||
Supplier’s Catalog No | IGX-RP1168 | ||
Supplier | ImuGeX | ||
Source antigen | E. coli | ||
Reactivity | Human | ||
Cross reactivity | |||
Applications | |||
Molecular weight | 9 |
Storage | -70°C | ||
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Other names | PTH, Parathormone, Parathyrin<br/>Recombinant Human Parathyroid Hormone (PTH) | ||
Grade | |||
Purity | >95% as determined by SDS-PAGE | ||
Form | Lyophilized from a 0.2 μm filtered solution in PBS | ||
Reactivity life | 6 months | ||
Note | For reserch purpose only | ||
Purity | >95% as determined by SDS-PAGE | ||
Description | Parathyroid hormone is a circulating hormone that acts as the central regulator of calcium metabolism by directly targeting bone, kidney, and intestine. The classical concept of PTH action is that it regulates serum calcium levels by stimulating bone resorption. However, intermittent administration of PTH selectively stimulates bone formation. It is now known that PTH binds to its receptor PTH1R, and activates the G protein alpha subunits. Besides PKA and PKC activation, PTH also regulates MAPKs including p42/p44 ERKs, p38, and c-Jun N-terminal kinase subtypes. |
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