Recombinant Human IL36RN (IL1F5)
Catalog No : IGX-RP1171
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| Product name | Recombinant Human IL36RN (IL1F5) | ||
|---|---|---|---|
| Catalog No | IGX-RP1171 | ||
| Supplier’s Catalog No | IGX-RP1171 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 0 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | IL36RN FIL1D, IL1F5, IL1HY1, IL1L1, IL1RP3, Interleukin-36 receptor antagonist protein | ||
| Grade | |||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in Tris, NaCl and KCl | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | Human IL36RN (IL1F5) is one of the cytokines from the interleukin 1 family encoded by a cluster of genes on chromosome 2. All members of this family show a 12 beta -strand, beta -trefoil configuration. IL36RN is a secreted protein monomer which is also known as interleukin 36 receptor antagonist (IL36RA). This cytokine is predominantly expressed in keratinocytes and a variety of other cell types including brain leukocytes, dendritic cells and macrophage cell types. IL36RN has shown increased expression in lesional psoriasis skin and is thought to play a role in skin inflammation. IL1F5 is a specific antagonist of the IL1 receptor related protein 2 - mediated response to IL1F9. It is also known to specifically inhibit the activation of NF-Kappa-B transcription factor which is induced by IL1F6. | ||
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