Imugex

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Categories: Peptides & Proteins / Proteins

Storage			-70°C
Other names			Interleukin-7
Grade
Purity			>95% as determined by SDS-PAGE
Form			Lyophilized from a 0.2 μm filtered solution in PBS
Reactivity life			6 months
Note			For reserch purpose only
Purity			>95% as determined by SDS-PAGE
Description			IL7 is a hematopoietic growth factor constitutively produced by stromal cells from the bone marrow and thymus. It is critical for B and T cell development and survival. IL7 promotes the differentiation of hematopoietic stem cells to lymphoid precursor cells by binding to a receptor composed of common gamma chain and IL-7Ra (CD127). Lymphoid precursor cells give rise to T cells, B cells, and natural killer cells. Furthermore, IL7 provides signals to regulate the survival of naive and memory CD4+ and CD8+ T cells NK T cells, innate lymphoid cells, and T regulatory cells. During B-cell development, IL7 also provides signals to promote survival, proliferation and differentiation. Recombinant mouse IL7 is a non-glycosylated protein with a molecular mass of 15.2 kDa.