Recombinant Human Galectin-3 (LGALS3)

Catalog No : IGX-RP1175
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Product name Recombinant Human Galectin-3 (LGALS3)
Catalog No IGX-RP1175
Supplier’s Catalog No IGX-RP1175
Supplier ImuGeX
Source antigen E. coli
Reactivity Human
Cross reactivity
Applications
Molecular weight 26.1
Storage -70°C
Other names IgE-Binding Protein, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen
Grade
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS.
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description Gal-3 interacts, via its lectin domain, with glycoproteins and glycolipids on the surface of animal cells. It has been shown that nuclear Gal­3 can modulate gene expression while cytosolic Gal­3 can inhibit apoptosis and participate in exocytosis. Gal-3 is generally expressed by the epithelial cells of many tissues as well as by inflammatory cells. An increased level of Gal-3 expression may lead to some lymphomas, as well as thyroid and hepatic carcinomas while the down-regulation has been associated with breast and colon cancer.