Recombinant Human GDNF
Catalog No : IGX-RP1176
328.74€
0.00€
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| Product name | Recombinant Human GDNF | ||
|---|---|---|---|
| Catalog No | IGX-RP1176 | ||
| Supplier’s Catalog No | IGX-RP1176 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | Human | ||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 15 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | GDNF, Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor, ATF<br/>Recombinant Human Glial-Derived Neurotrophic Factor (GDNF) | ||
| Grade | |||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from a 0.2 μm filtered solution in Sodium Citrate and NaCl (pH 4.0) | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | GDNF is a disulfide-linked, homodimeric neurotrophic factor that belongs to the cystine-knot family of growth factors. Natively glycosylated, GDNF signals through a multi-component receptor system that comprises of a RET and one of the four GFRα receptors. In embryonic midbrain cultures, GDNF promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. Mature rat and human GDNF exhibit approximately 93% amino acid sequence identity and show considerable species cross-reactivity Recombinant Human GDNF is a non-glycosylated, disulfide-linked homodimer (30 kDa) consisting of 135 amino acids in each subunit. | ||
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