Recombinant Human PTHLH/PTHrP
Catalog No : IGX-RP1181
1165.55€
0.00€
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| Product name | Recombinant Human PTHLH/PTHrP | ||
|---|---|---|---|
| Catalog No | IGX-RP1181 | ||
| Supplier’s Catalog No | IGX-RP1181 | ||
| Supplier | ImuGeX | ||
| Source antigen | E. coli | ||
| Reactivity | |||
| Cross reactivity | |||
| Applications | |||
| Molecular weight | 0 | ||
| Storage | -70°C | ||
|---|---|---|---|
| Other names | Parathyroid hormone-related protein, Parathyroid hormone-like protein, PLP, PTH-rP | ||
| Grade | |||
| Purity | >95% as determined by SDS-PAGE | ||
| Form | Lyophilized from 0.2 μm filtered solution in PBS | ||
| Reactivity life | 6 months | ||
| Note | For reserch purpose only | ||
| Purity | >95% as determined by SDS-PAGE | ||
| Description | PTHLH is a member of the parathyroid hormone family which regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth via its receptor, PTHR1. In most cases of humoral hypercalcemia of malignancy, PTHLH is responsible. Alternatively spliced transcript variants have been found for this gene and mutations in this gene are also associated with brachydactyly type E2 (BDE2). Furthermore, evidence have been found for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone. | ||
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