Recombinant Human EPO

Catalog No : IGX-RP1185
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Product name Recombinant Human EPO
Catalog No IGX-RP1185
Supplier’s Catalog No IGX-RP1185
Supplier ImuGeX
Source antigen HEK293
Reactivity Human
Cross reactivity
Applications
Molecular weight 20
Storage -70°C
Other names Erythropoietin<br/>Recombinant Human Erythropoietin-Alpha (EPO)
Grade
Purity >95% as determined by SDS-PAGE
Form Lyophilized from a 0.2 μm filtered solution in PBS (pH 7)
Reactivity life 6 months
Note For reserch purpose only
Purity >95% as determined by SDS-PAGE
Description EPO is predominantly synthesized and secreted by tubular and juxtatubular capillary, endothelial, and interstitial cells of the kidney. Approximately 10-15% of the total amount of Epo comes from extrarenal sources and is predominantly produced by hepatocytes and Kupffer cells of the liver. Approximately 40% of the molecular mass of Epo is due to its glycosylation. Glycosylation is an important factor determining the pharmacokinetic behavior of Epo in vivo. Non-glycosylated Epo has an extremely short biological half life. It still binds to its receptor and may even have a higher specific activity in vitro.