Imugex

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Categories: Biochemicals / Biochemicals

Storage			-20°C
Other names
Grade			Molecular Biology Grade
Purity			≥99% (TLC)
Form			Supplied as a liquid at 10mM in DMSO.
Reactivity life			12 months
Note			For reserch purpose only
Description			An anti-inflammatory glucocorticoid. Inhibits the expression of the inducible but not the constitutive nitric oxide synthase in vascular endothelial cells (IC50=5 nM). Enhances active cation transport in aortic smooth muscle cells by stimulating the Na+-K+ pump. Has anti-inflammatory and anti-rheumatic properties. Induces apoptosis in human thymocytes. In general, 500-1000 nM of dexamethasone is sufficient to induce apoptosis following a 6-hour incubation at 37°C. Appearance: Supplied as a liquid at 10mM in DMSO. Purity: ~99% Recommended Dilution: 1000X dilutions for inducing apoptosis in Jurkat cells. Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.